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Are Digestive Problems Caused By GMO's and Roundup? - Episode 126

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In this week's episode...

In this special episode, Jeffrey is joined by Dr. Michelle Perro and Stephanie Seneff where they will discuss whether digestive problems are caused by GMO's and Roundup.  What's special about this episode is that they will take one disease at a time and discuss whether GMOs and Roundup are causing that disease or exacerbating it.

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Notes for this week's Podcast
This week's Transcript


Speaker 1: (00:07)
Hello, everyone. And welcome. I am so excited about this lecture, what we are going to do today. Been done before anywhere. In fact, I don't think I've for lectures with so much time and intention. I have 30 pages around me right now for this lecture. Why do I have that? I've spoken about GMOs a thousand times in 45 countries, but we're doing something different here. We are going to take one disease category at a time. And to discuss the question, whether GMOs and Roundup are contributing to that disease, causing it, exacerbating it, et cetera. Now we're gonna do this in a way that's different than most, or perhaps any type of lecture you've seen because this is designed really to be cut up into pieces so that when it hits the social media, there's one short, uh, video, just about metabolic disorders. One short video about digestive disorders, one about reproductive so that you and the audience can share it and send it around and make it viral.

Speaker 1: (01:18)
A lot of the real truth about health videos are going viral. There's one that was least with me last week, or last month, it's got over 175,000 views. So what we're going to do with, uh, these experts that I'm so honored to be with, uh, doctors, Michelle per and Stephanie set, is we're going to introduce a disease, introduce the ever, and then talk about what could possibly be causing it from GMOs in Roundup. Then we're gonna go to a new disease. And some of what you're going to hear is repetitious, because remember when it gets cut up by Ben and send around the world, they won't have the benefit of what they just heard. When we talked about cancer. When we're now talking about out, um, atopic diseases. So you are gonna hear some repetition, but bear with us, you're gonna learn it better. And the people who are going to hear about it are gonna learn it for the first time. And they may actually make the decision to go organic, to get rid of the GMOs and the Roundup. So I wanna say that the, I love the of you, Stephanie and Michelle. You are heroes, uh, rock stars in this. You have seen the, um, plausible causative pathways. You've seen what's happening, uh, Stephanie in the deep research that you're doing in the big data, Michelle in your actual practice. And so we get to pour the, your experiences and wisdom into this. Anything you wanna say before we take this for a test drive,

Speaker 2: (02:53)
I'd say let's rock it. Jeffrey. We're ready. All right. All right.

Speaker 1: (02:56)
All right. So we're gonna start with digestive disorders. Here we go. Are your digestive problems caused by GMOs and Roundup? There's a lot of digestive problems that are plaguing people in the United States. And thanks to doctors, Nancy Swanson, this definit Senate, we have some correlational evidence showing a rise in both the increased use of Roundup on genetically and UN soy and corn and inflammatory bowel disease. This is correlation. It doesn't prove causation, but it shows a remarkable correlation which we will and discussed to see. Is it possible that inflammatory bowel disease is being exacerbated in the us population by the use of Roundup. We also have

Speaker 1: (03:53)
Adjusted age adjusted deaths due to intestinal infection, going up very closely in the slow of the increased use of glyphosate applied to soy and corn, and finally peritonitis going up as well. So I could tell you as, as a way of introduction that I asked people at 150 lectures, including about 2000 medical conference is how many people, what do people get better from when they switched to non GMO and largely organic diets? And the number one most common result was always digestive disorders. Cause they, someone would say, you know, GERD or acid reflux or inflammatory balance and who else notices a digestive disorder improvement. And that was always huge numbers. In fact, we then surveyed 3000, 256 people who got better from 28 different conditions. And sure enough digestion was at the top 85.2% described an improvement when they switched to non GMO organic. And it wasn't just a small improvement, 80% of those that reported had these a significant improvement nearly gone or completely recovered. So this was big. So I would like to hear first from you, Michelle, you've been doing pediatrics for close to 40 years. So you were around before GMOs and Roundup were introduced. Did you see an increase in digestive or disorders soon after GMOs were introduced in the late 1990s? And have you found that changing the diet back so that people do not so that children do not have GMOs in Roundup in their diet can undo some of that damage?

Speaker 2: (05:41)
Uh, yes. Jeffrey. So it was, is you're right. 40, 40 years harder, hard. Imagine practicing. I am a frontline doc, meaning I actually take care of kids in offices and I actually put my hands on them and examine them. I know, kind of shocking that I touch, touch the children. And what happened is around the early two thousands, all of a sudden, you know, being an, an astute pediatrician, asking parents questions, listening to parents that I started seeing sick and sicker children. And remember what we as pediatricians do largely has to do, especially with babies, eating pooping and sleeping. I spend most of my life talking about those three issues. So food and poop are a huge part of my conversation almost daily. So in the early two thousands, yes, indeed. Chronic diseases across the board, let's hone in just on gut issues or gastrointestinal or GI for short, everything was going up chronic abdominal pain in kids.

Speaker 2: (06:37)
That's the number one pain complaint in children, constipation. Um, a third of kids now are reporting pooping issues, altering with diarrhea, known as IBS in adults, kids with reflux, which means their food comes up in the back of their throats. And many parents are unaware because the kids think it's normal. So when I ask the kids, does your food come back in your throat? And then you have the solid back down and they say, yeah, all the time. And the parents go, what? So reflux is on the rise and bloating tummies. I have toddlers who look like they're five months pregnant, big bloated tomies and we can go on, then start mucking around with the diet. And the first thing I do is put all the kids in our organic diet. A lot of parents are say, there's no way that this can be, I'd say you do the experiment.

Speaker 2: (07:28)
You are, you are in of four you're four family members. See what happens. And lo and behold, some kids is really quick, three days longer for most about four weeks. And the O well, majority begin to get better. Varies, depends on what we're dealing with, of course, but not only the kids get better, but their family members get better because you don't give little Suzy, a kale salad, and everyone else is eating pepperoni pizza that doesn't work. So the whole family has to change their diet and lo and behold, oh my gosh, everyone's not running to the, you know, supermarket to buy laxatives and, you know, um, and acids, everyone felt better.

Speaker 1: (08:09)
You know, your experience when you talked about the five months pregnant reminded me of a photo in their film, secret ingredients, where the families switched to organic and the bloating and the large stomachs went away. The constipation went away. The digestive issues, the moods, as a result in the children, Stephanie, you've been examining the, um, chemical properties of glyphosate and its modes of action in the body. What would you say would be some of the reasons why may contributing to the problems of digestion in the United States?

Speaker 3: (08:45)
It's a huge list and it's hard to know how to say it quickly. I have a whole chapter in my book on the gut. In fact, that was a very difficult chapter to write. I, I, I read enormous number of papers. There's so much coming out on the gut and all the different correlations with different species and different diseases. It's very hard to untangle it all and get the story straight. But I feel like I did in my book and it's, um, it's an astonishing, uh, all the things it's like so many, it starts, of course, with the fact that glyph is a preferentially kills, the beneficial bacteria, the bacteria have this enzyme, EEPs P sys in the, in this biological pathway called the Chiate pathway. And, um, we don't have that enzyme. And that's why it's claimed the glyphosate is safe, but in fact, it's not safe because these are our microbes. Have the enzyme, use the enzyme to make aromatic amino acids, which are essential amino acids. As our bodies can't make them.

Speaker 1: (09:36)
Let me, let me, let me unpack that just for a second. So Monsanto's been bragging for years that their herbicide kills plants because it blocks their pathway that we don't have, and they're being sued right now because they knew all along that bacteria that's inside us need that pathway in order to produce the precursors to the happy molecules, the happy, the happy serotonin, melatonin and dopamine. So that's been confirmed that the gut bacteria, when it's blasted with Roundup can disable that function. Go ahead, Stephanie.

Speaker 3: (10:14)
Right. And so, and then studies on which microbes were most affected by glyphosate found that LCIS and BI bacteria, which are really important, you know, they're the healthy, uh, microbes that we need to be able to the baby needs in order to be able to digest the milk it needs, these microbes. And those microbes are really getting hit hard by glyphosate. Whereas there's other species like salmonella and clot that are robust against glyphosate. So you get that imbalance where these pathogens are overgrowing in the gut, even get overgrowth of yeast because of our microbes being reduced, the bacteria beginning reduced in number of the yeast overgrowth. Also the yeast feast on the foods, the sugars that we're, um, we're unable to digest these foods properly so that they end up, um, causing this yeast overgrowth and, um, which is part of the problem. And then you get this Cevo is quite interesting, uh, you know, small intestinal bacterial overgrowth, which is quite, uh, becoming an epidemic.

Speaker 3: (11:10)
And that one's interesting to me. And also that goes with the, uh, diarrhea and constipation, the cycles of diarrhea and constipation, all the bloating, all the stuff off it's. Um, there was a, uh, woman who tried to commit suicide by drinking glyphosate. And, and there was a report about her, a paper that was published. And one of the things they found striking was that it paralyzed her gut, it completely paralyzed it. And, um, and that doesn't surprise me. One of the things that serotonin and serotonin is important for, for getting the, the gut to move the Fe sees down the tube, but also, um, myin is a, is a contractile protein. That's very important in the gut to push things through myin has critical dependencies on glycine residues that can get disrupted by glyphosate and cause that molecule not to contract quite amazing, there was a study that showed a single glycine in that critical glycine in that protein, if it gets replaced by something else, actually a, which is very similar to glycine. Um, the, the, the pro the, the protein can only contract at 1% capacity just with that small change.

Speaker 1: (12:11)
Right? So, so what we're seeing is let's gonna, we're gonna make line these up. Okay. First of all, we mentioned that glyphosate, which is the chief poison in Roundup. So everyone knows Roundup is something that is not just used on lawns. It's sprayed on food, it's sprayed on most genetically engineered crops. It's sprayed on a lot of the grains and beans in the United States aids. It's it's, you can find it in wine, in beer, in orange juice because of how it's used chemically. And so

Speaker 2: (12:40)
We're and infant formula.

Speaker 1: (12:42)
Thank you, Michelle infant formula. You have to be the, the baby whisperer. You speak on behalf of the babies in the next generation, just dive in when you speak when they can. So it turned, it's not only patented as a herbicide, but it's patented also as an antimicrobial, as an antibiotic, but it like no other antibiotic that I know about searches and destroys the good stuff, not the bad stuff, right. And this was actually shown by Karen Christian, an expert on the microbiome who took a and model and applied Roundup, and sure enough dramatic negative changes, dramatic negative changes in the microbiome when exposed to Roundup. And I asked him about what could those changes do in terms of digestive, or for example, inflammatory by, and he has a number of things which I'll share in a moment, but so we've talked about the changes in the gut bacteria, which can decimate and change the population. And you talked about the changes in the motility, or the ability for it to contract. So if it's just paralyzed, that's gonna be a problem with digestion.

Speaker 3: (13:53)
That's CIBO because the bacteria get back to up too. I mean, the whole thing isn't moving through, so you get all this food up high that's, uh, allowing the bacteria to grow there, cuz it's, uh, in the small intestine, you're getting overgrowth of bacteria in that sea condition. And then of course the diarrhea comes in, the kids are constipated, they constipated, they constipated finally they get all this water and then it just gues out. It's a sort of reaction to the C to try to wash the food out because you can't contract the, the muscles to get it out. So you have to find another way. So it's this constant cycle of constipation and diarrhea.

Speaker 1: (14:26)
Is that what you're seeing Michelle as well?

Speaker 2: (14:29)
Um, I am. And, um, and you know, there's also this all sorts of related issues. We're seeing kids where they still withhold and then they to get blocked up and then they get this leakage around there and that's a big problem now. And then they get the mood disorders related around it because of the gut bacteria I balances, which we'll talk about later and that affect their mood. So it becomes cyclical. I also wanna add just when you were talking about the microbiome and these gut disorders, which is the leading cause, um, you know, the Roundup is way more toxic. Glyphosate is a nightmare and it's horrific and causes chronic toxicity, but the adjuvants, the POA, the other stuff in Roundup, these emulsifiers they're Sants, they break down fats, emulsify have an equally destructive effect on the microbiota. There's a lot of literature now on emulsifiers found in all sorts of processed food products. So when we talk about going organic, we talk about removing processed foods to get rid of those emulsifiers because Roundup has a dual nasty action. Uh, both the glyphosate, which is a, um, antimicrobial and the emulsifying action of dis surfactant, which is an antimicrobial effect. So both

Speaker 3: (15:42)
And, and those surfactants allow glyphosate to get into the cell too. They promote the uptake of glyphosate. So that's really important too. And I think the processed foods have so many chemicals in them. I think it's really important to emphasize eating whole foods, as well as eating organic foods.

Speaker 1: (15:58)
You know, I was talking to farmers who took animals off of GMOs that have been sprayed with Roundup and they noticed a dramatic change in the digestive condition, uh, in Patterson from Denmark eat, you both know him, or we both know of him. He, he changed the diet to non GMO soy for his pigs. And didn't tell his farm man. And about, uh, soon after the, the farm man came and said, you changed the, the feed and IBB said, uhoh what happened. And he said, no more diarrhea in the piglets they had in tractable uncontrollable diarrhea for two years, it was killing a lot of the piglets and within a day or so, they were not having diarrhea. And I interviewed the farmers having this experience at the same time, I went to a practitioner who was talk and their patients interviewing their patients about I B D and IBS.

Speaker 1: (16:53)
And it was like talking about the same thing only they were using different terms in the humans as the animals. And what was interesting about the animal study is they didn't shift to organic. They, uh, they didn't shift to non-processed foods. So it really, it was, uh, an easier conclusion to draw. But when you start looking at some of the resu, there is so much evidence. I can, I can totally understand Stephanie, why there's too much to put in the digestive chapter. I wrote an article that was peer reviewed and published in the international journal of human nutrition and functional medicine and gathered all the ways that GMOs and Roundup could contribute to disorders of the gut. And it was quite a, so I wanna share with you now what Karen Christian said about the, about inflammatory bowel research and what he found about the microbial community inside humans.

Speaker 1: (17:46)
So he said in a very large sta scale, uh, paper on irritable bowel disease published in 2017, they compared people who had I B D with those that didn't. And they found that those that did had really low diversity in the microbiome. And when he applied Roundup to the human model for microbiome, there was a dramatic reduction in the biodiversity. Diversity is so important in the health of the microbiome. So that was one thing. Second short chain, fatty acids, which are produced by the microbiome are very important. When you have low for short chain, fatty acids, irritable bowel is very common and that was driven Dr. Decrease in short chain, fatty acids. The only thing he did different was add Roundup to the gut. In addition, there's some Keystone strains, there's one whose name I'm gonna butcher, uh, fecal bacterium, PR nit. Maybe you can pronounce it better. Right? I interview,

Speaker 3: (18:49)
I just call

Speaker 1: (18:50)
It Dr. F I say, he's a, it's a superhero. We're just gonna call it Dr. F well, that's well established to protect against inflammatory bowel, and it is driven down because of the Roundup. There's also an increase in ammonia for a number of reasons. And it's interesting that GMOs alone, even without Roundup have been linked to an increase in pneumonia in ammonia and ammonia is an inflammatory agent in the bowel. And it's very toxic to the liver and it screws up the metabolic functions of all sorts of micro microbials. And there's a rising pH. Now when there's a rising pH, the digestive enzymes fall apart. So now they can digest the food which increases the ammonia, et cetera, et cetera. So just based on what he saw in the human microbiome exposed to Roundup gave all these indicators for inflammatory bowel. So I'm gonna go back to both of you. We'll start with Stephanie, give another one other piece about why Roundup might be causing digestive, and then I'll throw it back to you, Michelle. And we'll talk about some of the research of GMOs in Roundup causing digestive disorders. Go ahead.

Speaker 3: (20:04)
Yeah. And I talked about both the ammonia and the, um, acid, um, going up the pH going up. That's really very interesting. I found some data on looking at, uh, the guts of children way back when, before glyphosate and that the, uh, pH was much lower consistently across the population than, than it is now. Uh, and that is the ammonia. And that is the consequence of the, uh, proteins not getting digested. Glyphosate was found, Anthony Samso ordered up, um, samples of trips and PEPs and lipase from a chemistry lab. And he tested them for glyphosate. They were from a pig, they were sourced from a pig and they all three CA high levels of glyphosate in them. I think glyphosate is getting into those digestive enzymes and messing up their ability to work. And so the, um, so the body actually can't digest the proteins, the, the, the, the enzymes that are supposed to digest the proteins don't work correctly and also the fats.

Speaker 3: (20:56)
And so both of them become problematic when the proteins don't get digested in the upper gut, they end up as peptide sequences in the lower gut, you know, in the, um, in the, in the, the lower large bowel. And that's where you have these microbes breaking down those proteins and turning amino acids into ammonia, cuz that's amino acids have nitrogen. So that's how you get this excess ammonia, which also raises the pH because ammonia has a very high pH and then acetate is, is underrepresented. That's one of those short chain, fatty acids, abut eight acetate and prop pro propionate, which I always have trouble saying those three are so crucial and those are produced by the gut microbes from the roughage. These are things that we're not, don't normally digest. Um, and that if that's messed up too, then you've got sort of the roughage becomes, um, harsh because it's now being broken down by the, by the microbes into those short chain mean acid.

Speaker 3: (21:48)
And the buterade is absolutely essential for providing food for the gut, uh, lining the, the cells in the, um, in the large intestine love ate that's their favorite food. And they depend upon the microbes to produce a supply of buterade. And when they don't have enough, buterade bad things happen, you get the leaky gut situation and inflammatory gut of those problems. Um, because those, um, cells are not being well fed by the berate. That's not being produced by the microbes. There's just a, a lot of things a study was done recently that showed the glyphosate causes leaky gut. And that was also because of these undigested proteins, which end up irritating the gut and cause an overproduction of a protein called Zul and Zolin actually opens up the gut barrier. So when you have these EST proteins and the leaky gut, those peptides can leak past the gut barrier and get into the general circulation.

Speaker 3: (22:39)
And the immune cells get very upset when they see that they see these foreign proteins wandering around the blood, they produce antibodies to those proteins. And when they do that, those antibodies can become auto antibodies, attacking human cells through this process called molecular mimicry where the, uh, human protein has a sequence that resembles a sequence that was in the original peptide from a food source that didn't get broken down. That's the whole gluten intolerance thing. I mean, I think the whole epidemic and gluten intolerance is a consequence of the gluten not being properly digested the gluten molecules, getting out into the circulation, causing immune reaction and then causing, uh, immune attack on human proteins through this molecular mimicry process.

Speaker 1: (23:21)
Certainly when we talk about digestion, we need to talk about leaky gut and also this autoimmune disease issue. That's on the rise, Michelle, what's your ex, both from clinical experience and your extensive knowledge of research, uh, where do you want to take it up in terms of the gut? You wanna pick it up from the RPOD post eye research. So the leaky gut research pick it, pick your poison. Oh,

Speaker 3: (23:42)
So much. Um,

Speaker 2: (23:42)
That was a great segue from Stephanie's comments. Um, I'll pick it up in terms of this inflammatory bowel disease, because prior to maybe 15, 20 years ago, we didn't see a lot of inflammatory bowel disease in kids. And now it's on the rise. That's Crohn's ulcers, ulcerative colitis. And what I'm seeing, particularly, even in babies is early signs of colitis, where they have mucus in the stools. Mucus is a not a normal fine. And what we do know is that depleted trip tofa has been found in, in patients with I B D inflammatory bowel disease. And as we know is that's where indeed glyphosate inhibits in the production of those aromatic amino acids, such as trip tofa, which has been found to be very depleted in patients with inflammatory bowel disease. So it's really important. We cannot make those amino acids. Some, we can make some, we can't those aromatic amino acid where glyphosate blocks the Chimay pathway, which Stephanie referred to before are key and crucial for the production for so many functions in the body.

Speaker 2: (24:40)
And, and particularly in the hormones that controlled mood like depression. And we can talk, talk about that later, and that's called serotonin. So I wanna get back to babies for a second. Why is that? Because the cutting edge of research, as, as Karen will say, and Stephanie is the microbiota within the first three years of life, you are able to manipulate and alter your microbiota. After about 890 days, that's no longer possible. You might have a little bit of wiggle room. I've read anywhere up to 30% where you can change it. I'm not sure if that's true or not, because there's a lot we don't know about the microbiome. So what's set up for baby in those first three years is key. And what you feed baby. If the baby's not having breast milk, they will not get enough of the microbiome from mom. If they're fed for formula, even if you add it, it's not enough babies from a hundred years ago, their fecal smears look like a monoculture of a type of beneficial bacteria called bifido bacteria.

Speaker 2: (25:38)
And we know that glyphosate based herbicides target these acid loving bacteria, like bifido like GLAC basil, you need this BI bacteria. That's the name to lower the pH of the poop. When you lower the pH of the intestine and the poop that prevents the growth of pathogens. This is a life saving life, protecting nourishing aspect of nourishment for baby by what's in the poop via a vaginal birth passage through the, um, the canal breastfeeding and formula. Not quite good enough, we do it sometimes. But just to understand, if you have to use formula, you'll have to use organic cuz there's glyphosate. And if you do a soy formula, that's not organic. There are GMOs in glyphosate, in a formula, but just blows my mind. So you want to protect the baby's microbiota. Um, and that microbiome, as we know, is important for detoxification immune health, production of vitamins, et cetera, et cetera. And we can go into that further. And so you wanna create this balance robust microbiota when you check kids. Now, when you check adults now and you actually do an assay and look at the composition of their stool, you find a loss of diversity. You find high levels of pathogens or potential pathogens. You find losses of digestive enzymes. You've find markers, early markers of inflammation that are like a crystal ball for who's gonna go on develop autoimmune disease. And all that info is right in the stool. That was well said. Thank you.

Speaker 4: (27:23)
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